Several differences may account for these divergent outcomes, including radiation dose (15 Gy vs. 9 Gy), animal age (2–3 months vs. 6 months), post irradiation assessment time of behaviors (2 weeks vs. 4–6 weeks), behavioral tasks used (anxiety-like behaviors/Y-maze vs. object recognition/fear conditioning), and different CSF1R inhibitor used (PLX3397 vs. PLX5622). The gene discussed is CSF1R; the disease is Anxiety.