Additionally, PI3K mRNA levels increased in BC patients (P = 0.0003, q = 0.0006), and PAK1 (P = 0.0093, q = 0.0098) and GZMH (P = 0.0001, q = 0.0004) mRNA expression showed a threefold increase in BC patients compared to controls. Here, PAK1 is linked to breast cancer.