To strengthen our hypothesis that NUP98::KDM5A-expressing AML cells depend on intact DNA damage repair to ensure protection against the accumulation of excessive DNA damage, we measured the levels of the DNA damage marker phosphorylated H2A.X59 in a dTAG-GFP-NUP98::KDM5A cell line (Table 1). The gene discussed is NUP98; the disease is acute myeloid leukemia.