More importantly, we employed the xenografted mice and found that although knocking down KHSRP inhibited breast tumor growth, the tumor growth inhibition effect from SB-T-101141 was also abolished in KHSRP-depleting cells, indicating that KHSRP acts as at least one of the targets of SB-T-101141 (Figs. 6H–J and S6I). The gene discussed is KHSRP; the disease is breast neoplasm.