Thus, we checked the counterpart of MAPK pathway-related cell stress responses and unveiled that SB-T-101141, rather than Paclitaxel, prominently exerted ER stress-related GTPase activating protein (SH3 domain) binding protein 1 (G3BP1) granule aggregation, without affecting G3BP1 expression (Figs. 8B and S7A), suggestion of a partial function of SB-T-101141 on breast tumor cell death via ER stress. The gene discussed is G3BP1; the disease is breast neoplasm.