Following this, the expression levels of apoptosis-related genes (BAX, Bcl-2), an angiogenesis gene (VEGF-C), a gene associated with progression and development (HIF-1α), genes involved in the EMT pathway (SNAIL and E-Cadherin), and a prostate cancer marker (KLK3) were evaluated using Real-Time PCR. This evidence concerns the gene HIF1A and Familial prostate cancer.