Other differential diagnoses are neurofibroma (CD34, SOX10 and S100 +), perineurioma (EMA, CD34 and GLUT1 +), connective tissue nevus (more sclerotic, CD34 +, SMA -/+), blue nevus (melanocytic markers), fibroblastic subtype of plexiform fibrohistiocytic tumor/plexiform myofibroblastoma (SMA +, CD34 and desmin ±), pilar leiomyoma and smooth muscle hamartoma (smooth muscle markers), and plaque-like myofibroblastic tumor (short fascicles of myofibroblastic cells, wiry collagen bundles, SMA +, factor XIIIA +) [6, 27–30, 37]. This evidence concerns the gene SOX10 and neurofibroma.