Rompré-Brodeur et al. conducted a study indicating that the integration of radiation therapy with anti-PD-L1 therapy in a murine bladder cancer model led to substantial tumor regression at both irradiated and non-irradiated sites, emphasizing enhanced cytotoxic T-cell infiltration and a tumor microenvironment transformation that promotes cytotoxic activity [31]. The gene discussed is CD274; the disease is urinary bladder carcinoma.