However, the antioxidant GSH, which is overexpressed in tumor cells, scavenges ROS and serves as a substrate for glutathione peroxidase 4 (GPx‐4) to catalyze the reduction of phospholipid hydroperoxides, thereby reducing the accumulation of lipid peroxides and protecting tumor cells from oxidative damage mediated by the ferroptosis pathway.[13]. The gene discussed is GPX4; the disease is neoplasm.