CCND1 and colonic neoplasm: Prior studies have also linked miR‐15a‐5p regulation of CCND1 and CDK6 to cancer biology, suggesting a broader relevance of this regulatory axis: Zhao found that the expression level of miR‐15a‐5p in pancreatic cancer was negatively correlated with CDK6 through bioinformatics analysis [38], whereas Li demonstrated that hsa‐miR‐15a‐5p alleviated the proliferation, migration and invasion of colon cancer by targeting the CCND1 gene [39].