CEACAM5 and colorectal carcinoma: The results also revealed an association between the D50 values and CEA levels: a higher D50 and Shannon entropy level were found in patients with normal CEA in both CRC (p = 0.014 and 0.02, respectively) and NSCLC patients (p = 0.005 and 0.006, respectively), while the Simpson index did not show statistical significance (Table 2, Figure S3).