The green cluster is mainly related to the pathogenesis, treatment, and prognosis of HCC, including hepatocellular carcinoma, mechanism, metabolism, activation, pathway, prognosis, immunotherapy, etc. The red cluster is related to the specific processes that include apoptosis, oxidative stress, lipid-peroxidation, ROS, and nrf2. This evidence concerns the gene NFE2L2 and hepatocellular carcinoma.