Using the TISIDB portal, the association of LRFN4 with immune subtypes was examined across various cancers, including ACC, BLCA, BRCA, CESC, CHOL, KIRP, KIRC, LIHC, LUAD, LUSC, PAAD, PRAD, SARC, STAD, TGCT, THCA, and UCEC (Figure 8). This evidence concerns the gene LRFN4 and adrenal cortex carcinoma.