RASSF1 and neoplasm: Ras-association domain family 1A (RASSF1) is an important oncogene in the family of homoboxes, family 1A (RASSF1A) is a novel tumour oncogene cloned from the short arm of human chromosome 3, and its high methylation is highly correlated with the degree of differentiation of malignant tumours, which is often predictive of low patient survival [6].