A survey of Cauca sians with diabetes mellitus demonstrated that the allele C of polymorphism rs2074192, allele G of polymorphism rs4240157 and allele T of polymorphism rs4646188 of ACE2 gene are correlated with hypertension in males, and the allele G of polymorphism rs4240157 has an association with hypertension in females [18]. This evidence concerns the gene ACE2 and hypertensive disorder.