Similar to previous reports by our group and others, we also observed preferential co-occurrence of other gene mutations with U2AF1R156/Q157 (e.g., ASXL1) or U2AF1S34F (e.g., BCOR) mutations in MDS patients (Fig. 8B and Supplementary Tables 19–20).15,16. The gene discussed is ASXL1; the disease is myelodysplastic syndrome.