USP8 and neoplasm: The highest CADD scores were observed for a variant in the G protein coupled receptor 162 [GPR162 (NM_019858.2, c.652A > T p.R218*)] in the right tumor (CADD score 40) and for a variant in ubiquitin specific protease 8 [USP8 (NM_001128610.3, c.1724C > A p.P681Q)] in the left tumor (CADD score 31), respectively (Supplementary Table-2) (8).