Polymorphisms in CYP3A4, CYP2C19, and CYP1A2 could impair detoxification of environmental toxicants, while dysfunction in CYP2E1 and CYP2D6 has been linked to oxidative stress and mitochondrial impairment—both implicated in neurodevelopmental delays. This evidence concerns the gene CYP1A2 and Neurodevelopmental delay.