For example, DDX3X is overexpressed in breast, colorectal, lung, medulloblastoma, and prostate cancers,4, 8 whereas it is somatically mutated in medulloblastoma, melanoma, and non‐Hodgkin lymphoma subtypes, such as natural killer/T‐cell lymphoma (NKTCL), Burkitt's lymphoma (BL), and diffuse large B‐cell lymphoma (DLBCL).4, 9, 10, 11, 12. The gene discussed is TNFRSF10B; the disease is diffuse large B-cell lymphoma.