We conducted a secondary analysis of the AKI sequencing dataset GSE225192 downloaded from the Gene Expression Omnibus (GEO) database and found that, compared with the non-AKI group, the expression levels of tumor necrosis factor receptor‐associated factor (TRAF)‐interacting protein with forkhead‐associated domain (TIFA) and interleukin-1 beta (IL-1β) were upregulated in the AKI group. The gene discussed is TIFA; the disease is acute kidney injury.