DSCAM and autism spectrum disorder: Similarly, DSCAM loss-of-function mutations show a relatively high frequency in autism spectrum disorder (ASD) patients, and Dscam deficiency leads to abnormal voluntary locomotor control and ASD-like behaviors in mouse models (Lemieux et al., 2016; Laflamme et al., 2019; Xu et al., 2011; Chen et al., 2022; Lim et al., 2021).