Based on TCGA database, we performed pan‐cancer expression analysis of PRMT5 mRNA and found that PRMT5 mRNA was upregulated in tumor tissue than adjacent nontumor tissue in most cancers, including pancreatic cancer (Figure 1A; pancreatic ductal adenocarcinoma [PAAD], the green dash‐line box). The gene discussed is PRMT5; the disease is familial pancreatic carcinoma.