RAN and cerebellar ataxia: In the Eg. P29/pCMV-4flag group, the enriched biological functions were mainly cadherin binding, nucleocytoplasmic carrier activity, Ran GTPase binding, and ATPase activity (Figure 1C) and the enriched KEGG pathways were mainly RNA transport, spinocerebellar ataxia, glycolysis, and protein processing in the endoplasmic reticulum (Figure 1D).