YTHDF3 and non-small cell lung carcinoma: For instance, in non-small cell lung cancer (NSCLC), YTHDF3 preferentially binds to the m6A sites on YAP pre-mRNA, while YTHDF1 and YTHDF2 competitively bind to respectively promote YAP translation or degradation, ultimately determining YAP protein levels and influencing tumor progression 68.