For instance, in non-small cell lung cancer (NSCLC), YTHDF3 preferentially binds to the m6A sites on YAP pre-mRNA, while YTHDF1 and YTHDF2 competitively bind to respectively promote YAP translation or degradation, ultimately determining YAP protein levels and influencing tumor progression 68. This evidence concerns the gene YTHDF2 and non-small cell lung carcinoma.