NFKB1 and escherichia coli infection: A study on the neuroinflammatory response mediated by Escherichia coli infection suggested that inhibition of Escherichia coli-induced miR-146a in vivo may further promote the production of inflammatory cytokines, exacerbate astrocyte and microglial reactivity, and shorten the survival time of mice via the toll-like receptor/NF-κB or epidermal growth factor receptor/NF-κB signaling pathways159.