Indeed, similar to neurodegenerative diseases, accumulation of proteins such as ubiquitin, (phosphorylated) tau protein, transactive response DNA–binding protein 43 kDa (TDP‐43) and p62 has been identified in muscle biopsies of IBM patients, especially in advanced stages of the disease [24, 25, 26, 27, 28]. This evidence concerns the gene TARDBP and inclusion body myositis.