STING1 and cancer: Drug repurposing, or repositioning,is a strategic approach toidentify new therapeutic uses for existing drugs, offering a fasterand more cost-effective alternative to traditional drug development., Lamivudine, a nucleoside reverse transcriptase inhibitor (NRTI)prescribed to treat Human Immunodeficiency Virus (HIV) and hepatitisB, has shown potential in oncology, by inducing necroptosis and DNAdamage, stimulating interferon gene (STING) pathway activation, andinhibiting mechanisms that can help overcome cancer resistance toconventional therapies.−, , , , ,