This observation comes in agreement with the previously reported elevated expression levels of other members of the ADAM family in other cancer types, such as ADAM10/12/17 in early gastric cancer [45], ADAM8/9/15 in primary multiple myeloma [46] and ADAM12 in colorectal cancer [47] as well as breast and liver cancer [48]. This evidence concerns the gene ADAM12 and AL amyloidosis.