GO analysis showed genes which influence tumor microenvironment by modulating the activity of immune cells like macrophages (S100 A11, FCGR3 A, C1QB), microglia, and T cells, as well as promoting inflammatory signaling (SRGN) that supports tumor growth, invasiveness, and resistance to therapies (Wang et al. 2021; Feng et al. 2024; Manou et al. 2024). This evidence concerns the gene C1QB and neoplasm.