Next, to investigate the effect of mutant p53 on GD3S expression, we knocked down p53 in BC cell lines with different p53 mutations (Hs578T, HCC38, BT549, HCC1395, HCC1143, HCC70, and MDA-MB-468) by transient overexpression of shRNA targeting p53 mRNA (Fig. S4A). This evidence concerns the gene TP53 and breast cancer.