Because METTL1, METTL3, METTL14, and METTL16 were significantly associated with AML development in the previous reports, we set METTL1 as the baseline due to its lowest expression level among these four genes, and focused on the METTL proteins above the expression level of METTL1. The gene discussed is METTL1; the disease is acute myeloid leukemia.