To assess the utility of ExIF for interrogating EM cell state plasticity, we amplified EM state diversity in A549 lung cancer cells by comparing control cells to those treated for 48 h with either EGF (0.1 μg/mL) or TGF-β1 (0.01 μg/mL); growth factors known to weakly or strongly (respectively) drive EMT in A549 cells39. The gene discussed is TGFB1; the disease is lung cancer.