Some paediatric/mixed-age studies pre-date the discovery of the GATOR1 complex genes (roles in epilepsy described for DEPDC5 in 2013 [105] and NPRL2/3 in 2016 [43]), and paediatric/mixed-age studies do not included DEPDC5 or NPRL3 in the gene panels tested, including the largest study (involving 8565 individuals [106]) included in the 24 combined NGS studies reported by Symonds et al. [103]. Here, DEPDC5 is linked to epilepsy.