CD274 and melanoma: Notably, CD155 and CD276 were significantly more frequently and more highly expressed than CD274 in SLN DCCs (P < 0.0001, Fisher’s exact test; Fig. 6b), primary tumors, metastases31,36, melanoma cell lines32,37, human epidermal melanocytes35 and mouse melanoma models33 (Extended Data Fig. 9f,g).