Additionally, we observed significantly higher numbers of both OVA-specific and TRP-2-specific CD8 + T cells (TRP-2 being a B16F10 neoantigen) in the draining lymph nodes of the primary B16F10-OVA tumor (Fig. 6p, q), supporting the induction of a multivalent antigen-specific immune response. Here, CD8A is linked to neoplasm.