From the biosynthetic pathways underscored by these significant changes (Fig. 7b) and by inferring corresponding data from the KEGG pathway (www.genome.jp) and reactions analysis (www.lipidmaps.org), it is deducible that the ST3GAL5, ST8SIA1, B4GALNT1, B3GALT4, ST3GAL1, B4GALT1-4, and GCNT2 enzymatic pathways are significantly increased with PD. The gene discussed is ST8SIA1; the disease is Parkinson disease.