The univariate Cox proportional hazards regression analysis identified MARCH8 (p = 0.015), embolus (p = 0.034), tumor encapsulation (p = 0.028), tumor differentiation degree (p = 0.008), tumor size (p = 0.031), and Barcelona Clinic Liver Cancer (BCLC) stage (p < 0.001) as predictive variables (Fig. 1H). This evidence concerns the gene MARCHF8 and neoplasm.