CD8A and neoplasm: For example, Peroxisome Proliferator-Activated Receptor gamma (PPARγ) inhibitors can induce disulfidptosis in oral squamous carcinoma cells by upregulating SLC7A11, thereby promoting the recruitment of classical Dendritic Cells (cDCs) and CD8+ T-cells into the tumor microenvironment, ultimately suppressing tumor progression.24