Furthermore, APOL1 is abundantly transcribed in the placenta, autoantibodies against APOL1 have been demonstrated in the blood of women with preeclampsia, and APOL1 transgenic mice develop a pre-eclamptic phenotype, increasing biological plausibility of an association (Wen et al. 2013, Elliott et al. 2014, Bruggeman et al. 2016). Here, APOL1 is linked to preeclampsia.