SMARCB1 and viral infectious disease: PBRM1 is a chromatin modulator of the SWI/SNF chromatin remodeling complex, which includes SMARCA4, SMARCB1, SMARCC1, ARID1A, DPF2, and SMARCE1, also implicated in ACE2 expression regulation and, thus, in host cell susceptibility to viral infection (63).