In recent years, these biomarkers have received significant attention in cardiovascular and oncological surgeries as independent predictors of mortality and morbidity.7,11-14 Multi-inflammatory index, which was first reported in the literature by Casadei Gardini et al12, is a new inflammatory prognostic marker with high clinical value, derived from hematological and biochemical parameters NLR and CRP values to predict the prognosis in patients with metastatic colorectal cancer. The gene discussed is CRP; the disease is metastatic colorectal cancer.