Specifically, lncRNA MEG3, which has been implicated in neurodegeneration including AD, PD, and HD (Balusu et al. 2023; Chanda et al. 2018; Quan et al. 2020), showed an early upregulation at 48H with its expression returning to baseline by 168H (Figure S3D). This evidence concerns the gene MEG3 and Parkinson disease.