Biomarker comparisons between IPA (216 cases) and CPA (72 cases) using the Mann-Whitney U test revealed significant differences in NEU% [Z = 3.102, p = 0.002, 89.0 (82.2–94.1) vs. 82.1 (74.6–90.2)] and IL-6 [Z = 3.712, p < 0.001, 57.0 (19.8–228.1) vs. 23.5 (7.3–65.7)]. Here, IL6 is linked to Ito hypomelanosis.