CTU2 and cancer: ROC curve analysis demonstrated that CTU2 has high diagnostic accuracy (AUC > 0.8) for eight cancer types, including READ, LUSC, LUAD, kidney renal papillary cell carcinoma (KIRP), KIRC, kidney chromophobe (KICH), COAD, and bladder urothelial carcinoma (BLCA) (Figure 3C).