At the protein level, CTU2 was upregulated in 9 datasets across 8 cancer types in the CPTAC database, including clear cell renal cell carcinoma (CCRCC), COAD, GBM, hepatocellular carcinoma (HCC), head and neck squamous cell carcinoma (HNSC), lung squamous cell carcinoma (LSCC), LUAD, and pancreatic ductal adenocarcinoma (PDA) (Figure 1G). Here, CTU2 is linked to head and neck squamous cell carcinoma.