GH1 and optic papillitis: Adrenal suppression: alternate-day steroid therapy.Impairment of stature: steroids sparing agents and growth hormone therapy.Osteoporosis: Calcium supplementation, vitamin D, and use of steroid-sparing protocols.Peptic ulceration: H2 blockers.Hypertension: antihypertensive agents.Cataract: low dose and short duration of steroids treatment, regular examination by ophthalmologists.Increased intracranial pressure: investigate papilledema.Behavioral changes: reduce or withdraw steroids.