Notably, CD93 (OR: 1.138, 95% CI: 1.024-1.265, P = 0.016), GCNT2 (OR: 1.177, 95% CI: 1.058-1.310, P = 0.003), HSD17B13 (OR: 1.134, 95% CI: 1.024-1.255, P = 0.015), and PIGN (OR: 1.097, 95% CI: 1.014-1.186, P = 0.021) showed a strong association with the risk of PCOS. This evidence concerns the gene HSD17B13 and polycystic ovary syndrome.