The Renca cells co‐cultured with 3T3 cells were grafted subcutaneously into the BALB/c mice in four groups (Ctrl, AAV‐GSN, αPD‐1 and AAV‐GSN + αPD‐1, n = 5), and GSN overexpression lentivirus was constructed to upregulate the GSN expression in CAFs, which were later injected into the subcutaneous tumour models (Figure 7A). This evidence concerns the gene GSN and neoplasm.