Based on the significant enrichment in coagulation, regulation of response to wounding and wound healing (Fig. 3), we identified 15 genes (F5; F11; THBD; SH2B3; F9; KLKB1; PLCG2; FGB; VWF; FGA; ADAMTS13; F2; ST3GAL4; PROC; PLEK) for further analysis to elucidate their potential roles in DVT pathogenesis. The gene discussed is KLKB1; the disease is deep vein thrombosis.