Module overarching ontologies and correlation helped identify broad protein functions more closely associated with C9orf72 (M5-Extracellular matrix/Heparin binding) as well as the degree to which these functions overlapped (i.e. all ALS subgroups correlated to M7-Cytoskeleton/Microglial and M10-Ubiquitination/Gluconeogenesis). Here, C9orf72 is linked to amyotrophic lateral sclerosis.