Although postprandial (i.e. high glucose) glucagon hypersecretion has been described early in type 1 diabetes disease progression [29], short-term cytokine exposure did not appear to reflect a type 1 diabetes phenotype with regards to the hypoglycaemic state (low glucose), characterised by reduced glucagon secretion [2, 30, 31]. The gene discussed is GCG; the disease is type 1 diabetes mellitus.