Other exposures appeared more specific with respect to the outcome dimension, where risk factors tapping into mental health (e.g., ADHD, bipolar disorder, schizophrenia) were more specific to cognitive function, and biomarker traits (e.g., creatinine levels, sex hormone binding globulin, insulin-like growth factor 1) mostly to specific physical function. The gene discussed is SHBG; the disease is bipolar disorder.